منابع مشابه
Adverse effects of statins.
In October last year we published an article by John Abramson and colleagues that questioned the evidence behind new proposals to extend the routine use of statins to people at low risk of cardiovascular disease. Abramson and colleagues set out to reanalyse data from the Cholesterol Treatment Trialists’ (CTT) Collaboration. Their contention was that the benefits of statins in low risk people we...
متن کاملPotential adverse effects of statins on muscle.
M any people have high blood cholesterol that may lead to coronary heart disease (CHD). A multifaceted approach consisting of diet, exercise, and pharmacological management is recommended to lower the risk of CHD.1 Elevated low-density lipoprotein-cholesterol (LDL-C) has been established as a major cause of CHD.1 The group of cholesterol-lowering drugs known as statins (3-hydroxy3-methylglutary...
متن کاملRemembering Statins: Do Statins Have Adverse Cognitive Effects?
The issue of statin-associated cognitive impairment has been a hot topic among both patients and health care providers, especially since the U.S. Food and Drug Administration (FDA) issued a statement regarding rare postmarketing reports of ill-defined cognitive impairment associated with statin use. This statement was based on case reports, and no objective measures of cognitive function were u...
متن کاملAdverse side effects of statins in the oral cavity.
UNLABELLED Increased plasma levels of cholesterol are high risk factors of cardiovascular disease. Statins are drugs that inhibit cholesterol synthesis at both pancreatic and extrahepathic levels, being the treatment of choice for hypercholesterolemia. OBJECTIVE To analyze the side effects of statins in the mouth cavity, and to analyze the symptoms after interruption of the treatment. DESIG...
متن کاملPharmacogenomics of statins: understanding susceptibility to adverse effects
Statins are a cornerstone of the pharmacologic treatment and prevention of atherosclerotic cardiovascular disease. Atherosclerotic disease is a predominant cause of mortality and morbidity worldwide. Statins are among the most commonly prescribed classes of medications, and their prescribing indications and target patient populations have been significantly expanded in the official guidelines r...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2005
ISSN: 1811-7775
DOI: 10.3923/ijp.2005.210.225